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WHAT CAUSES DEMENTIA?
A HETEROGENOUS MIX OF FACTORS
RISK TRACKS
BrainSpa TM has organized a growing body of evidence for the various factors that increase or decrease a participant's susceptibility to cognitive loss or dementia . This disparate array of factors has been logicaly organized into an ontology that makes risks understandable, meaningful, and actionable
SURVEY-GENETIC-CLINICAL
dynamic CAPABILITIEs
Risk for cognitive loss is non-absolute. What's absolute is that any provider may debate our interpretation of what the evidence shows regarding risk. For this reason, BrainSpa intends to offer providers the flexibility of customizing our model parameters to reflect their views of what the evidence supports for participant's under their care
CONNECTED COMMUNITY OF PEERS
BIOLOGIC
LIFESTYLE
MEDICAL
ENVIRONMENTAL
three pronged data capture
Data points for participant risk are captured utilizing three sources to ensure a comprehensive assessment of risk. A digital survey is the starting point to capture the participant's personal, medical and family histories. This initial assessment of risk is enhanced with optional genetic and clinical lab assessments
ADJUSTABLE MODEL INPUTS AND PARAMETERS
open for input
Open to peer communities. Our risk assessment application allows for contributions from scientific and medical peers. Providers may submit their own model parameters, powered by published or non-published data for reveiw by their peers
LOW
RISK MODIFIABILITY CONTINUUM
HIGH

EXPOSURES PAST AND PRESENT INCLUDING EDUCATION AND CURRENT OCCUPATION
YOUR RISK STARTING POINT SUCH AS
GENETICS, GENDER AND AGE

HIGHLY MODIFIABLE RISK FACTORS INCLUDING DIET AND NUTRITION, EXERCISE, AND SOCIAL INTERACTION
CONDITIONS THAT REQUIRE MEDICAL MANAGEMENT LIKE HYPERTENSION AND DYSLIPIDEMIA

RISK IS MEANINGFULL AND ACTIONABLE WHEN YOU KNOW WHAT IS IN AND OUT OF YOUR CONTROL


LIFESTYLE
MEDICAL
ENVIRONMENTAL
BIOLOGICAL
BRAINSPA ORGANIZES RISK ONTO LOGICAL TRACKS
RISK APPROACH
WHAT WE OVERCOME
A DISCONNECTED EXPERIENCE
THE PROBLEM
Current state of the art risk assessments rarely assess more than one domain of risk and do not present results in an understandable, meaningful or actionable way
GENETIC TESTING
YOU TESTED POSITIVE
YOU TESTED NEGATIVE
Positive is good, right?
Negative is bad, right?
"No not really, sorry about the news. Please take a brochure."
CLINICAL TESTING
"No, you are in the clear! Oops, forget to mention your poor diet"
YOU HAVe met syndrome
don't have met syndrome
Ok, now what?
Ok, now what?
"Sorry about the news, here are several prescriptions."
HISTORY
"No, you are in the clear! Oops, forget to mention your high BMI."
Now what?
YOU ARE HIGH RISK
Now what?
YOU ARE LOW RISK
Now what?
"Sorry about the news. Read this blog and try to live healthier."
"Your in the clear. Carry on as usual."
CURRENT STATE OF THE ART IS DISCONNECTED
BRAINSPA IS COMPREHENSIVE
OUR APPROACH
SURVEY OF
HISTORIES
CLINICAL
TESTING
GENETIC
TESTING
Comprehensive assessment of risk considers inherited as well as non-inherited factors. For this reason, BrainSpa includes genetic testing and lab testing along with a comprehensive understanding of each participant's historical exposures to non-inherited hazards

FOR A PARTICPANT'S RISK TO BE UNDERSTANDABLE, RISKS MUST BE PRESENTED ALONG THE CONTINUUM OF THEIR LIFESPAN AND RELATIVE TO THE OVERALL RISKS OF THE POPULATION

RISK IS MEANINGFUL AND ACTIONABLE WHEN YOU UNDERSTAND WHAT IS IN AND OUT OF YOUR CONTROL
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